The Ministry of Health analyzes the vaccine acquisition process to define smallpox immunization strategy

With the threat of abekopper spread, the Ministry of Health already evaluating the process of acquisition vaccines, to then define an immunization strategy in Brazil. There is no stockpile of the immunizer in the country when the disease was eradicated in the 1970s.

As there is no own vaccine that protects against monkey pox (monkey pox), the World Health Organization (WHO) recommends an immunizing agent that works against traditional smallpox (smallpox) as long as it is more up-to-date, second or third generation (which are not replicated in the human body). This type of drug proved to be 85% effective against monkey pox, guaranteed device.

There is a vaccine in use in some countries that is already highly rated. It is called Jynneos (in the USA), Imvamune (in Canada) or Imvanex (in Europe) and is manufactured by the Danish laboratory Bavarian Nordic. The immunizer was approved in 2019 by the US Food and Drug Administration (FDA) and in 2013 by the European Medicines Agency (EMEA).

In Brazil, however, the product has not yet received a registration request from the National Health Surveillance Agency (anvisa).

Each new drug or vaccine, before being released for use in the country, requires authorization from the National Health Surveillance Agency (anvisa). Despite this being the normal procedure, the agency informed that so far there are no requests for vaccines or medicines against monkey pox in Brazil. The initiative must come from pharmaceutical laboratories.

Jynneos are unable to replicate in the human body, are less likely to cause side effects than conventional vaccines and have been shown to be effective in inducing a potent immune response. Those not previously vaccinated against smallpox should receive two doses at 28-day intervals. But it is still unclear about the duration of the protection.

Despite being cited, the vaccine is not widely available. Faced with the growing cases of monkey pox in the world, Bavarian Nordic announced that they have increased the production of the immunizer. However, the Ministry of Health did not state which vaccine is being analyzed for procurement.

This week, the Minister of Health Monitoring in the Ministry of Health, Arnaldo de Medeiros, reported that the federal government is negotiating to buy an immunizer that protects against smallpox, but has not given further details. The statement came in an interview with the portal metropolises.

According to Medeiros, a meeting has even been held with the production company, and the acquisition has been mediated by the Pan American Health Organization (PAHO). The expectation, he said, is that the doses will reach the country between the third and fourth quarters of this year.

Who can be vaccinated

The World Health Organization (WHO) does not recommend mass vaccination of the population against monkey pox. According to the device, only priority groups should receive the immunization agent, such as laboratory workers exposed to the virus and people who had close contact with infected people.

Also, according to the WHO, measures to control and diagnose the disease, in addition to vaccinating specific groups, can prevent a worldwide outbreak.

What are the symptoms of monkey pox?

The symptoms are less similar to those seen in elderly smallpox patients: fever, headache, muscle and back pain in the first five days. Then there are eruptions – in the face, palms and soles of the feet -, lesions, pustules and finally crusts.

How is it transmitted?

Infection in early cases is due to direct contact with blood, body fluids, lesions on the skin or mucous membranes of infected animals. Secondary person-to-person transmission may result from close contact with infected airways secretions, lesions on the skin of an infected person, or objects that have recently been contaminated with biological fluids or materials from a patient’s wounds.

health risk

According to experts, monkey cups should not have the same dimension as covid-19. According to scientist Ester Sabino, a professor at the University of São Paulo (USP) and leader of the group responsible for the first sequencing of the virus in Brazil, this virus that causes smallpox in monkeys does not have air transmission, as does the coronavirus. .

– The monkey cups need very close contact so that people can be infected. Therefore, monkey cups are unlikely to have the same dimension as Covid, ”he said in a statement. interview with the newspaper O Estado de S. Paulo.

confirmed cases in Brazil

Brazil currently has five confirmed cases, three in São Paulo, one in Rio Grande do Sul and one in Rio de Janeiro. Eight cases are still under investigation. There was one death under investigation in Minas Gerais, but it was discarded this Wednesday (15) for monkey pox by the Ezequiel Dias Foundation. This is a 41-year-old man, with no travel history and no contact with a suspected or confirmed case of the disease. The causes of death are still under investigation.


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